Per data final
des de
fins
Per malaltia
Per entitat
Per estat
Per país
Per promotor
Phase I Clinical Study of Dose-escalation Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of Recombinant Anti-FGFR Hum...
Zhejiang Newind Biotechnology Co.
Esophageal Neoplasms; Stomach Neoplasms
Inici:
18/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/II Clinical Study of Mitoxantrone Hydrochloride Liposomes in Combination With Gemcitabine, Dexamethasone, and Cisplatin in Relapsed/Refractory...
Peking Union Medical College Hospital, CAMS
CSPC Pharmaceutical Group Co./CSPC Ouyi Pharmaceutical Co.
Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral
Inici:
01/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Single arm and single center clinical study on safety, tolerance and efficacy of GC101 injection in patients with type 1 spinal muscular atrophy
(Other Hospital/Academic/Medical Center)
GeneCradle
Spinal Muscular Atrophy
Inici:
16/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study on the Safety and Efficacy of Specific TIL-TCM Cells for Advanced Relapse-refractory or Metastatic Pancreatic Cancer
Shanghai Biomed-Union Biotechnology Co.
Pancreatic Neoplasms
Inici:
02/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study of Safety and Tolerability of Melphalan Hydrochloride for Injection in the Treatment of Relapsed or Relapsed and Refractory Multiple My...
CASI Pharmaceuticals {EntreMed}
(Other Hospital/Academic/Medical Center)
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
26/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I study of ZS801 injection, an rAAV gene therapy drug of Sichuan Zhishan Weixin Biotechnology Co., Ltd., in hemophilia B subjects.
Sichuan Zhishan Weixin Biotechnology Co.
Blood Coagulation Disorders; Hemophilia B; Hemostatic Disorders
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study of TAA05 Injection in the Treatment of Adult Patients With FLT3-positive Relapsed/Refractory Acute Myeloid Leukemia
PersonGen BioTherapeutics (Suzhou) Co.
Leukemia, Myeloid, Acute
Inici:
09/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Open-label Study Evaluating the Safety, Tolerability and Preliminary Efficacy of XYF13 Car-T in the Patients With Recurrent Glioblastoma.
(Other Hospital/Academic/Medical Center)
MingMed Biotechnology Co./Xi'an Yufan Biotechnologies Co.
Glioblastoma
Inici:
10/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Comparative Study of the Combined Effect of Temozolomide with Nilotinib and Temozolomide Alone on Non-surgical Newly Diagnosed Human Glioblastoma Mult...
(Other Hospital/Academic/Medical Center)
Sobhan Pharmaceutical Factory
Glioblastoma
Inici:
09/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Trial for the Safety and Efficacy of BCMA-targeted CAR-T Cells Therapy for Refractory/Relapsed Multiple Myeloma
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
20/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A multi-center, open-label, balanced, randomized, two-treatment, two-period, two-sequence, two-way crossover, multiple-dose, steady-state bioequivalen...
MSN Laboratories
Carcinoma, Renal Cell; Kidney Neoplasms; Wilms Tumor
Inici:
02/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of CD70-targeting CAR-T Therapy in the Treatment of CD70-positive Advanced/Metastatic Solid Tumors
Chongqing Precision Biotech Co.
Carcinoma, Renal Cell; Kidney Neoplasms; Neoplasm Metastasis; Neoplasms; Ovarian Neoplasms; Uterine Cervical Neoplasms; Wilms Tumor
Inici:
31/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of CD70-targeting CAR-T Therapy in the Treatment of Advanced/Metastatic Renal Cell Carcinoma
Chongqing Precision Biotech Co.
Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Neoplasm Metastasis; Wilms Tumor
Inici:
31/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
This is a Phase I Clinical Study to Evaluate the Safety and Efficacy of CAR-T Infusion Preparation in the Treatment of CD19-positive Relapsed/Refracto...
Chongqing Precision Biotech Co.
Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
06/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open, Single-armed, Phase I Study to Evaluate the Safety and Efficacy Using Autologous TIL in Patients With Advanced Malignant Solid Tumors
Shanghai Gencells Therapeutics Co.
Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug-Related Side Effects and Adverse Reactions; Head and Neck Neoplasms; Melanoma; Neoplasms; Uterine Cervical Neoplasms
Inici:
14/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of Anti-CEA CAR-T Therapy in the Treatment of CEA-positive Advanced Malignant Solid Tumors
Chongqing Precision Biotech Co.
Colorectal Neoplasms; Esophageal Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Recurrence; Stomach Neoplasms
Inici:
10/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, First-in-human Study of ARB202, Bispecific Antibody to CDH17 and CD3 in Advanced Gastrointestinal Malignancies
Arbele
Bile Duct Neoplasms; Cholangiocarcinoma; Cholangiocarcinoma; Colorectal Neoplasms; Gastrointestinal Neoplasms; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Stomach Neoplasms
Inici:
30/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II, Open-Label Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Activity of Tolinapant in Combination With Oral Deci...
Otsuka Holdings/Otsuka Pharmaceutical/Astex Pharmaceuticals
Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral
Inici:
23/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase Ib Clinical Trial to Evaluate the Efficacy and Safety of TQB2618 Injection Combined With Pembrolizumab in Patients With Relapsed or Refractory L...
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co.
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia
Inici:
01/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Early Clinical Study of SENL101 Autologous T Cell Injection in the Treatment of Adult Patients With Relapsed or Refractory CD7+ Hematolymphoid Maligna...
Avalon GloboCare/Hebei Senlang Biotechnology Co.
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
01/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of Anti-CEA CAR-T Therapy in the Treatment of CEA-positive Advanced Malignant Solid Tumors
(Other Hospital/Academic/Medical Center)
Chongqing Precision Biotech Co.
Colorectal Neoplasms; Esophageal Cancer; Esophageal Neoplasms; Neoplasm Metastasis; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms; Recurrence; Stomach Carcinoma; Stomach Neoplasms
Inici:
25/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/Ib Study Evaluating Single-agent Inavolisib and Inavolisib plus Atezolizumab in PIK3CA-Mutated Cancers
Roche {F. Hoffmann-La Roche}
Head and Neck Neoplasms; Neoplasms, Unknown Primary
Inici:
16/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Label, Dose-escalation, 12 weeks, Phase I Study to Evaluate Safety and Pharmacodynamics of Investigational Product (VT-Tri) after Allogeneic S...
ViGenCell
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
03/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Bioequivalence test of doxorubicin hydrochloride liposome injection
Qilu Pharmaceutical Co./Qilu Pharmaceutical (Hainan) Co.
Breast Neoplasms; Ovarian Cancer; Ovarian Neoplasms
Inici:
17/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
To Observe the Long-term Efficacy and Safety of Dual-target Chimeric Antigen Receptor T Cells in the Treatment of Refractory Relapsed B Cell Hematolog...
(Other Hospital/Academic/Medical Center)
Avalon GloboCare/Hebei Senlang Biotechnology Co.
Chronic Lymphocytic Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Unlog=C:\eq
Inici:
08/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Randomised, Open-Label, Single-Dose, Two-Treatment, Two-Way Crossover, Two-Stage Study to Evaluate the Bioequivalence of Onivyde (Irinoteca...
Ipsen
Adenocarcinoma; Pancreatic Cancer; Pancreatic Neoplasms
Inici:
30/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Dose Escalation Study of Mitoxantrone Hydrochloride Liposome Injection Combined with Cytarabine and Etoposide in the Treatment of Relapsed or ...
(Other Hospital/Academic/Medical Center)
CSPC Pharmaceutical Group Co.
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
01/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
VRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV)...
National Institutes of Health/National Institute of Allergy and Infectious Diseases
Moderna Therapeutics
Henipavirus Infections; Virus Diseases
Inici:
01/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Exploratory Study of alphaPD1-MSLN-CAR T Cells Secreting PD-1 Nanobodies for the Treatment of MSLN-positive Advanced Solid Tumors
(Other Hospital/Academic/Medical Center)
Shanghai Cell Therapy Group Co.
Bile Duct Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms
Inici:
30/10/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Prospective, Single-center, Exploratory Study of Low-Dose Cytarabine, Mitoxantrone Liposome Combined with Granulocyte Colony Stimulating Factor in t...
CSPC Pharmaceutical Group Co./CSPC Ouyi Pharmaceutical Co.
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
01/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of CHM 1101 in Patients with Recurrent or Progressive Glioblastoma
Chimeric Therapeutics
Glioblastoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of RG-6333 in Combination with Glofitamab in Patients with Relapsed/Refractory Non-Hodgkin Lymphoma (r/r NHL)
Roche
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I single-dose study to evaluate the pharmacokinetics of CORT113176 softgel capsules in healthy subjects
Corcept Therapeutics
Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis; Motor Neuron Disease
Inici:
17/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Study in Patients With Acromegaly or Functioning Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs) to Characterize the Pharmacokineti...
Debiopharm {Affinium Pharmaceuticals}
Acromegaly; Neuroendocrine Tumors
Inici:
18/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A randomized, single dose, open label, four-period, two-sequence, full-replicate, cross-over oral bioequivalence study between the test product, Rifap...
Cipla
Tuberculosis
Inici:
26/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Trial for Evaluating the Safety, Tolerance and Efficacy of GPC3-targeting LCAR-H93T Cell in Treatment of Advanced Hepatocellular Ca...
(Other Hospital/Academic/Medical Center)
Nanjing Legend Biotechnology Co.
Carcinoma; Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
19/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase Ib Study Evaluating the Safety and Efficacy of Autologous CD30.CAR-T in Combination With PD-1 Checkpoint Inhibitor (Nivolumab) in Relapsed or Re...
Bristol-Myers Squibb
Tessa Therapeutics {FF CanVac}
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma
Inici:
30/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Phase I Monocenter, Clinical Trial of NECVAX-NEO1 in Addition to Anti-PD-1 or Anti-PD-L1 Monoclonal Antibody Checkpoint Inhibitor Monot...
NEC Corporation/NEC OncoImmunity
Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Head and Neck Neoplasms; Kidney Neoplasms; Melanoma; Neoplasms; Neoplasms, Unknown Primary; Renal Cancer; Urethral Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor
Inici:
05/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of CCT3-AXL-0038 in Patients with Osteosarcoma and Soft Tissue Sarcoma
Exuma Biotech {F1 Oncology}
Ewing Sarcoma; Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A multicenter, randomized, open label, two treatment, three period, reference replicated, single-dose, crossover, bioequivalence study of Azacitidine ...
AbbVie/Allergan {Allergan/Actavis {Actavis {Watson Pharmaceuticals}}}
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
15/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Study of Bispecific T Cell Redirection Antibodies in Combination With Checkpoint Inhibition for the Treatment of Participants With Relapsed...
Johnson & Johnson/Janssen R&D {Johnson & Johnson/J&JPRD {Johnson & Johnson/Janssen-Cilag/Janssen Research Foundation}}
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
25/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II, Safety Confirmation and Double-blind, Placebo-controlled, Randomized Study of Relatlimab in Combination With Nivolumab and Bevacizumab i...
Bristol-Myers Squibb
Carcinoma; Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
05/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label, Randomized, Two-part Parallel Study to Compare the Pharmacokinetics of Single Subcutaneous Injections of Cendakimab Administere...
Bristol-Myers Squibb
Dermatitis, Atopic; Eosinophilic Esophagitis; Unspecified
Inici:
02/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multiple-dose, Randomized, Double Blind, Placebo-controlled, Dose-escalation Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, P...
Chengdu KeyMed Biosciences {Chengdu ConMed Biosciences}
Glomerulonephritis, IGA
Inici:
24/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
The Safety and Efficacy Study of Autologous Tumor-infiltrating Lymphocyte (TILs) Therapy Combined With Conventional Chemotherapy for Patients With Adv...
Avalon GloboCare/Hebei Senlang Biotechnology Co.
Glioblastoma
Inici:
15/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Randomized, Single-dose, Open-label, Two-part, Two-period, Cross-over Study to Compare the Pharmacokinetics, Safety and Tolerability of the Pediatric ...
Novartis
Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis; Huntington Disease; Motor Neuron Disease; Unspecified
Inici:
13/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase 1 open-label study of S-770108 in patients with idiopathic pulmonary fibrosis-safety, tolerability, and pharmacokinetics of repeated doses
Shionogi
Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis
Inici:
28/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1b Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Bemarituzumab in Combination With Other Anti-cancer Therapies in Subject...
Amgen
Esophageal Cancer; Esophageal Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
17/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1b/2a Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DISC-0974 in Participants With Myelofib...
Disc Medicine
Anemia; Myeloproliferative Disorders; Palliative Care; Polycythemia; Polycythemia Vera; Primary Myelofibrosis; Thrombocythemia, Essential; Thrombocytosis
Inici:
06/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Single-arm, Multi-center, Phase I/II Study to Evaluate the Safety, Tolerability, and Efficacy of AT101 (Anti-CD19 Chimeric Antigen Rece...
AbClon
Lymphoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia
Inici:
15/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-label Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-AIO, a Triple-targeted Cell Preparation Targeting CD19...
Institute of Hematology & Blood Diseases Hospital
Nanjing Legend Biotechnology Co.
Lymphoma; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia
Inici:
14/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Pilot Study of Siltuximab in Large Granular Lymphocytic Leukemia (LGLL)
H. Lee Moffitt Cancer Center and Research Institute
EUSA Pharma {Jazz Pharmaceuticals/EUSA Pharma {Cytogen}}
Chronic Lymphocytic Leukemia; Leukemia; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid
Inici:
29/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Trial of an Infusion of Autologous T Cells Genetically Engineered With a Chimeric Receptor to Target the Follicle-Stimulating Hormo...
H. Lee Moffitt Cancer Center and Research Institute
Anixa Biosciences
Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms
Inici:
30/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1 study of buntanetap in Frontotemporal Dementia.
Annovis Bio {QR Pharma}
Dementia; Frontotemporal Dementia
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-Ew) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein ...
Seattle Children''s Hospital
Umoja BioPharma
Ewing Sarcoma; Osteosarcoma; Sarcoma
Inici:
20/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
First-in-Human Study of the BCL-2 Inhibitor ABBV-453 in Biomarker-Selected Subjects With Relapsed or Refractory Multiple Myeloma
AbbVie
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
17/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of Autologous HBV-specific TCR-T Cell Therapy (SCG101) in Patients With HBV-related HCC
(Other Hospital/Academic/Medical Center)
SCG Science (Dalian) Co.
Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
14/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single-center, randomized, open-label, two-agent, single-dose, two-cycle, double-crossover, bioequivalence trail of test preparation Macitentan Tabl...
Nanjing Zeheng Pharmaceutical Technology Development Co.
Hypertension; Hypertension, Pulmonary
Inici:
15/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Randomized, Open-label, Parallel-group Study to Compare the Pharmacokinetic Properties of CSL312 Administered by Subcutaneous Prefilled Syr...
CSL Limited/CSL Behring/Vitaeris
Angioedemas, Hereditary; Pulmonary Fibrosis; Thrombosis; Unspecified
Inici:
04/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study of a Personalized Neoantigen Vaccine in Esophagus Cancer Patients Who Have Completed Adjuvant Therapy Following Neoadjuvant Therapy and...
(Other Hospital/Academic/Medical Center)
Hangzhou Neoantigen Therapeutics Co.
Esophageal Cancer; Esophageal Neoplasms
Inici:
02/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Two-part, Open-label, Clinical Study to Assess the Safety, Tolerability and Activity of Intravenous Doses of ICT01 in Combination With Low-dose Subc...
ImCheck Therapeutics
Colorectal Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms; Pancreatic Cancer; Pancreatic Neoplasms; Prostatic Neoplasms
Inici:
19/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Early Phase I Clinical Trial To Evaluate the Safety and Efficacy of Human Derived Anti-BCMA CAR-T Injection for Subjects With Relapsed/Refractory Mu...
(Other Hospital/Academic/Medical Center)
Hrain Biotechnology Co.
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
09/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/IIa, Open-Label, Dose-Escalation Study of the Safety and Efficacy of an Anti-CD38 Antibody Drug Conjugate (STI-6129) in Patients With Relap...
Sorrento Therapeutics
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
01/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Clinical Study of TQB2618 Injection in Combination With Demethylation Drugs in Patients With Recurrent/Refractory Acute Myeloid Leukemia, Myel...
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co.
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes
Inici:
29/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single- and Multiple-Dose Dose Escalation to Evaluate the Safety, Tolerability, Pharmacokinet...
(Other Hospital/Academic/Medical Center)
AceLink Therapeutics/AceLink Therapeutics (Suzhou) Co.
Fabry Disease
Inici:
09/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/IIa Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Antitumor Activity of JAB-21822 in Combination With JAB-3312 i...
Beijing Jacobio Pharmaceuticals Co.
Carcinoma, Ductal; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms
Inici:
14/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I clinical study of the safety, tolerability, and pharmacokinetics of injectable TB001 after single and multiple subcutaneous injections in heal...
(Other Hospital/Academic/Medical Center)
Shenzhen Turier Biotech Co.
Tuberculosis
Inici:
01/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Trial to Evaluate the Safety and Efficacy of IM96 CAR-T Cells Therapy in Patients With Advanced Digestive System Neoplasms
Beijing Immunochina Medical Science & Technology Co.
Colorectal Neoplasms; Digestive System Neoplasms; Gastrointestinal Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
10/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
CC-486 and Venetoclax for Acute Myeloid Leukemia
Bristol-Myers Squibb
University of Colorado
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
15/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label Phase 1, Pharmacokinetic and Tolerability Study of Tolebrutinib Given as a Single Dose in Adult Participants With Mild Hepatic Impairmen...
Sanofi
Multiple Sclerosis; Multiple Sclerosis, Chronic Progressive; Multiple Sclerosis, Chronic Progressive; Myasthenia Gravis; Relapsing-Remitting Multiple Sclerosis; Unspecified
Inici:
18/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Translational Phase I/II Dose-Escalation and Expansion Study to Determine Safety, Tolerability, and Recommended Phase II Dose of RSO-021 in Patients...
RS Oncology
Mesothelioma; Mesothelioma, Malignant; Neoplasms, Mesothelial; Neoplasms, Unknown Primary; Pleural Effusion; Pleural Effusion, Malignant
Inici:
04/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Multi-center Phase 1 Pharmacokinetic and Tolerability Study of Tolebrutinib Given as a Single Oral Dose in Participants With Renal Impa...
Sanofi
Multiple Sclerosis; Myasthenia Gravis; Renal Insufficiency
Inici:
23/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II, Single Center, Open-Label, Safety and Efficacy Study to Improve Anemia in Subjects on Enasidenib With Lower Risk Myelodysplastic Syndro...
Bristol-Myers Squibb/Celgene
Anemia; Leukemia; Leukemia, Myeloid; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Myelodysplastic Syndromes; Palliative Care
Inici:
12/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Double-Blind, Placebo-Controlled, Multi-center, Multiple Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics o...
Eisai
Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Systemic Lupus Erythematosus
Inici:
18/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study on the Safety and Effectiveness of CART Cells in the Treatment of Advanced Gynecological Tumors
(Other Hospital/Academic/Medical Center)
Innovative Cellular Therapeutics Co.
Carcinoma, Endometrioid; Endometrial Neoplasms; Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Uterine Cervical Neoplasms
Inici:
09/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of BMF-219 for the Treatment of Multiple Myeloma (MM) and Diffuse Large B-cell Lymphoma (DLBCL)
Biomea Fusion
Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Multiple Myeloma
Inici:
01/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Trial to Evaluate the Safety and Efficacy of IM92 CAR-T Cells Therapy in Patients With Advanced Gastric or Pancreatic Adenocarcinoma
Beijing Immunochina Medical Science & Technology Co.
Adenocarcinoma; Esophageal Cancer; Esophageal Neoplasms; Pancreatic Cancer; Pancreatic Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
15/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single-Arm, Dose-Escalating Phase I Clinical Study To Evaluate The Safety, Biodistribution And Preliminary Efficacy Of Recombinant Human PD-1 Antibo...
(Other Hospital/Academic/Medical Center)
Zhejiang Yangshengtang Biotech Co.
Glioblastoma
Inici:
07/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/Ib Study of ASP2138 in Participants With Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcino...
Xencor
Astellas Pharma/Astellas Pharma Global Development
Esophageal Cancer; Esophageal Neoplasms; Pancreatic Cancer; Pancreatic Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
07/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open label, Single-arm Clinical Study Evaluating the Safety and Efficacy of IBI346 Infusion in Relapsed/Refractory Multiple Myeloma
(Other Hospital/Academic/Medical Center)
Innovent Biologics (Suzhou) Co.
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
28/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1, Open-Label, Multiple-Dose, Parallel Study to Determine the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability o...
AstraZeneca/Alexion Pharmaceuticals
Anemia; Myasthenia Gravis; Paroxysmal Hemoglobinuria; Unspecified
Inici:
07/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open Label, Multi-centre, Two-treatment, Two-period, Two-sequence, Two-stage, Multiple Dose, Steady-state, Crossover, Bioequivalence Stu...
Novartis/Sandoz/Lek d.d.
Breast Neoplasms; Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms
Inici:
07/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
AMG 701 Expanded Access Program
Amgen
Multiple Myeloma; Unspecified
Inici:
25/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study on the Safety and Effectiveness of CLL1 CAR-T Cells in the Treatment of CLL1-positive Hematological Malignancies
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Acute Myelocytic Leukemia; Hematologic Neoplasms; Leukemia, Myeloid, Acute
Inici:
28/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Expanded Access Program Of TAS-116 (Pimitespib) In Patients With Advanced Gastrointestinal Stromal Tumor
Otsuka Holdings/Taiho Pharmaceutical
Gastrointestinal Stromal Tumors
Inici:
01/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
NKG2D CAR-NK Cell Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Hangzhou Cheetah Cell Therapeutics Co.
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
13/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Label Trial of BI 765063 in Combination With BI 754091 (Ezabenlimab) Alone or With BI 836880, Chemotherapy, or Cetuximab, in Patients With Rec...
Boehringer Ingelheim
Carcinoma; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Liver Cancer; Liver Neoplasms; Squamous Cell Carcinoma of Head and Neck
Inici:
25/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Early-Phase Open-label Study of Tolinapant and Radiation in Cisplatin-Ineligible Patients With Previously Untreated, Locally Advanced Head and Neck Ca...
(Other Hospital/Academic/Medical Center)
Otsuka Holdings/Otsuka Pharmaceutical/Astex Pharmaceuticals
Carcinoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck
Inici:
17/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I clinical study of the safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858 tablets in healthy subjects and the effect of fo...
Haisco Pharmaceutical Group Co.
Bronchiectasis
Inici:
19/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib, Open-Label, Multicenter, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of XMAB24306 in Combination With Daratumumab in...
Roche/Genentech
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
28/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Multicenter, Open-label Study of BMS-986403 in Subjects With Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphoc...
Bristol-Myers Squibb
Chronic Lymphocytic Leukemia; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
27/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multicenter, Open Label, Randomized, Balanced, Two-treatment, Two-period, Two-sequence, Single Dose, Cross-over Bioequivalence Study of Doxorubicin ...
Sun Pharmaceutical Industries
Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms
Inici:
20/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study on the Safety and Effectiveness of Autologous Hematopoietic Stem Cell Transplantation Combined With CAR-T Cells in the Treatment of Ref...
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
15/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study on the Safety and Effectiveness of CD38 CAR-T Cells in the Treatment of CD38-positive Hematological Malignancies
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Acute Myelocytic Leukemia; Hematologic Neoplasms; Leukemia, Myeloid, Acute
Inici:
28/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Clinical Study on the Safety and Effectiveness of Targeting CD7 Chimeric Antigen Receptor T Cells in the Treatment of Autoimmune Diseases
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Arthritis, Rheumatoid; Autoimmune Diseases; Colitis; Colitis, Ulcerative; Crohn Disease; Dermatomyositis; Dermatomyositis; Inflammatory Bowel Diseases; Polymyositis; Rheumatoid Arthritis; Ulcer
Inici:
15/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Double-blind, Placebo-controlled, Single-center, Single and Multiple Oral Dose Study to Evaluate the Safety, Tolerability, and Pharmacok...
Aculys Pharma
No disponible
Inici:
12/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1b, Single Ascending Dose, Randomized, Double-blind Study to Evaluate the Safety, Tolerability, and Activity of SAR439459 in Adults With Osteo...
Sanofi
Osteogenesis Imperfecta; Osteoporosis
Inici:
22/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of SGN-ALPV in Advanced Solid Tumors
Seagen
Carcinoma, Endometrioid; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Stomach Carcinoma; Stomach Neoplasms; Testicular Cancer; Testicular Neoplasms; Uterine Cervical Neoplasms
Inici:
21/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Trial to Evaluate the Safety and Tolerability of Fb-PMT in Patients With Recurrent Glioblastoma
NanoPharmaceuticals LLC
Glioblastoma; Glioma
Inici:
10/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label Phase Ia/Ib Dose Escalation and Expansion Cohort Study of SL-172154 (SIRPa-Fc-CD40L) in Combination With Azacitidine or With Azacitidine...
Shattuck Labs
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Preleukemia
Inici:
15/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Ascending Single Oral Dose, Double-Blind, Randomized, Placebo-Controlled Study Assessing The Safety, Tolerability, and Pharmacokinetics of DSP-0187...
Sumitomo Dainippon Pharma {Dainippon Sumitomo}
No disponible
Inici:
02/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Expanded Access of LOXO-260 in Participants With RET Mutant or RET Fusion Tumors Refractory to Prior RET Selective TKI Treatment
Eli Lilly/Loxo Oncology
Carcinoma, Non-Small-Cell Lung; Thyroid Neoplasms
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Exploratory Study of Fully Human Anti-GPRC5D Chimeric Antigen Receptor T Cells (CAR-GPRC5D) in Patients With Relapsed/Refractory Multiple Myeloma o...
(Other Hospital/Academic/Medical Center)
Nanjing Iaso Biotherapeutics Co./Shanghai Iaso Biotechnology Co.
Leukemia; Leukemia, Plasma Cell; Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
17/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II Pressure Enabled Regional Immuno-Oncology Study of Hepatic Arterial Infusion of SD-101 With Systemic Checkpoint Blockade for Hepatocellu...
TriSalus Life Sciences
Bile Duct Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cholangiocarcinoma; Liver Cancer; Liver Neoplasms
Inici:
02/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RO7443904 in Combination With Glofita...
Roche {F. Hoffmann-La Roche}
Lymphoma; Lymphoma, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
18/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Open-label, Multi-center Study to Assess Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of AZD7789, an Anti-PD-1 and Ant...
AstraZeneca
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma
Inici:
18/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Label, Phase Ib/II Trial of LVGN6051 Combined With Anlotinib in the Treatment of Locally Advanced, Metastatic or Recurrent Refractory Soft Tis...
Lyvgen Biopharma Holdings
Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
25/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study of Conjugated Antibody Redirecting Natural Killer (CAR-NK) Cells Targeting CD33 and CLL1 in Patients With Acute Myeloid Leukemia
(Other Hospital/Academic/Medical Center)
Imbioray (Hangzhou) Biomedicine Co.
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
30/11/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
CD7 CAR-T Cell Treatment of Relapsed/Refractory CD7+ T - Acute Lymphoblastic Leukemia/ Lymphoma
iCell Gene Therapeutics
Crane Precision Immunotherapy Co.
Hematologic Neoplasms; Leukemia; Leukemia, Lymphoid; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lympho??
Inici:
01/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
AUGMENT-102: A Phase I, Open-label, Dose-escalation Study to Evaluate Safety, Tolerability and Preliminary Anti-Leukemic Activity of SNDX-5613 in Comb...
Syndax
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
09/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II, Multi-Center, Open-Label Study to Evaluate the Safety, Tolerability, and Preliminary Anti-tumor Activity of TNG908 in Patients With MTAP...
Tango Therapeutics
Bile Duct Neoplasms; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Glioblastoma; Mesothelioma; Neoplasms; Neoplasms, Mesothelial; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms
Inici:
23/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Relative Bioavailability of 40 mg/0.4 mL of BI 695501 Compared to 40 mg/0.8 mL of BI 695501 Formulation Following Single Subcutaneous Administration i...
Boehringer Ingelheim
Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Hidradenitis Suppurativa; Inflammatory Bowel Diseases; Psoriasis; Psoriatic Arthritis; Rheumatoid Arthritis; Spondylitis, Ankylosing; Unspecified
Inici:
18/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Two-part, Randomized, Investigator- and Participant- Blinded, Placebo-controlled, Multiple Ascending Dose Study to Assess the Safety, Tolerability, ...
Novartis
Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Systemic Lupus Erythematosus
Inici:
15/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Clinical Study of a Fully Human BCMA-targeting CAR (CT103A) Combined With Selinexor in the Treatment of Patients With Relapsed/Refractory Extr...
(Other Hospital/Academic/Medical Center)
Nanjing Iaso Biotherapeutics Co.
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
01/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single Arm, Single Dose Study to Characterize the Biodistribution of 124I-Labeled AT-03 in Select Organs in Patients With Systemic Amyloidosis
Attralus
Amyloidosis; Immunoglobulin Light-chain Amyloidosis
Inici:
30/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase Ib Clinical Study to Evaluate the Safety and Efficacy of TQB2858 Injection to the Subjects With Recurrent/Metastatic Nasopharyngeal Cancer
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co.
Head and Neck Neoplasms; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms
Inici:
01/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ia Study to Evaluate the Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy of IBI345 in Patients With CLDN18.2-positive Solid Tumor...
Innovent Biologics (Suzhou) Co.
Esophageal Cancer; Esophageal Neoplasms; Stomach Carcinoma; Stomach Neoplasms; Unspecified
Inici:
13/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of CAR-T Cells in Patients with Multiple Myeloma and Acute Lymphoblastic Leukaemia (ALL)
Kolmar Korea/HK inno.N
Multiple Myeloma; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase 1 Randomized, Dose-finding Study to Evaluate the Safety, Tolerability and Immunogenicity of a Novel Malaria Vaccine, MSP3-CRM-Vac4All/ Alhydroge...
Vac4All
Malaria; Malaria, Falciparum
Inici:
01/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Human bioavailability of fixed-dose anti-tuberculosis compound preparations
Henan Kangli Medicine Technology Co.
Zhengzhou Shenghua Pharmaceutical and Food Technology Development Co.
Tuberculosis
Inici:
31/10/2012
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Study of Bomedemstat Combined With Maintenance Immunotherapy for Patients With Newly Diagnosed Extensive Stage Small Cell Lung Cancer (ES...
National Institutes of Health/National Cancer Institute
University of Washington
Imago BioSciences
Carcinoma; Carcinoma, Small Cell; Neuroendocrine Tumors; Small Cell Lung Carcinoma
Inici:
11/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label, Multi-Center, Phase Ib/II Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of Tetra-specific Antibody GNC...
Biokin Pharmaceutical/Sichuan Baili Pharmaceutical Co.
Biokin Pharmaceutical/SystImmune
Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
14/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Bioequivalence study of ethambutol hydrochloride tablets in healthy subjects
Guangdong Zhongsheng Pharmaceutical Co./Guangdong Huanan Pharmaceutical Group Co.
Tuberculosis
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Multicenter, Phase I Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Clinical Activity o...
Roche {F. Hoffmann-La Roche}
Glioblastoma
Inici:
05/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
To Evaluate the Multi-center, Open, Single-arm Phase I/II Clinical Study of Recombinant Humanized Anti-CD47/PD-1 Bifunctional Antibody HX009 Injection...
Hangzhou Hansi Biomedical Co.
Waterstone Hanxbio
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral
Inici:
31/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Clinical Study of PTX-061 in Patients with Acute Myeloid Leukaemia
Pleco Therapeutics
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A multicenter, open-label, phase Ib/II study of the efficacy and safety of F520 combined with lenvatinib in patients with advanced solid tumor
Lunan Pharmaceutical Group Corporation/Shandong New Time Pharmaceutical Co.
Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Endometrial Neoplasms; Kidney Neoplasms; Neoplasms, Unknown Primary; Urethral Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms; Wilms Tumor
Inici:
23/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 0/Ib, Single Center, Clinical Trial With an Expansion Phase of AZD1390 Plus Fractionated Radiotherapy in Recurrent WHO Grade IV Glioma Patient...
AstraZeneca
(Other Hospital/Academic/Medical Center)
Glioblastoma; Glioma
Inici:
09/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A single-dose, randomized, open-label, crossover bioequivalence study of ethambutol hydrochloride tablets and Ebutol in healthy subjects under fasting...
Shenyang Hongqi Pharmaceutical Co.
Tuberculosis
Inici:
23/10/2018
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open-Label, Multicenter, Two Treatment, Two Period, Two Sequence, Single Dose, Crossover Bioequivalence Study Of Doxorubicin Hydrochlori...
Alembic Pharmaceuticals
Ovarian Cancer; Ovarian Neoplasms
Inici:
01/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A single-dose, randomized, open-label, crossover bioequivalence study of ethambutol hydrochloride tablets and Ebutol in healthy subjects after meals
Shenyang Hongqi Pharmaceutical Co.
Tuberculosis
Inici:
28/10/2018
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized Phase I/ II Multicenter Study Evaluating Combination of Luspatercept in LR-MDS Without RS Having Failed or Being Ineligible to ESA
(Other Cooperative Group)
Bristol-Myers Squibb/Celgene
Myelodysplastic Syndromes
Inici:
18/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A randomized open-label single-dose double-crossover bioequivalence study of ethambutol hydrochloride capsules in healthy subjects on an empty stomach...
Shenyang Hongqi Pharmaceutical Co.
Tuberculosis
Inici:
19/11/2018
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1, First Time in Human Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of NST 6179 in Healthy Subjects
NorthSea Therapeutics
Liver Diseases; Short Bowel Syndrome
Inici:
07/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1 Randomized, Single Center, Double-Blind, Placebo-Controlled, Dose-Response Study to Evaluate the Safety and Immunogenicity of rVSV-Nipah Vir...
Coalition for Epidemic Preparedness Innovations (CEPI)
Public Health Vaccines
Henipavirus Infections; Virus Diseases
Inici:
10/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics of DZD8586 in Healthy Adult Participants
Dizal (Jiangsu) Pharmaceutical Co. (AstraZeneca and SDIC Fund Management Company joint venture)
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
09/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label, Single-Sequence Study to Evaluate Potential Disease-Mediated Drug-Drug Interaction With Selected Cytochrome P450 Substrates in ...
Bristol-Myers Squibb/Celgene
Eosinophilic Esophagitis; Esophagitis
Inici:
07/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Single arm and single center clinical study on safety, tolerance and efficacy of GC101 injection in patients with type 2 and 3 spinal muscular atrophy...
(Other Hospital/Academic/Medical Center)
GeneCradle
Muscular Atrophy, Spinal; Spinal Muscular Atrophy
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open, Multi-Center Phase Ib Clinical Study Of A166 For Injection In The Treatment Of HER2-Positive Locally Advanced Or Metastatic Gastric Cancer Or...
Sichuan Kelun Pharmaceutical Co./Sichuan Kelun Botai Biopharmaceutical Co.
Esophageal Cancer; Esophageal Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
15/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Clinical study on the Safety and efficacy of CART cells in the treatment of Advanced Pancreatic Cancer
(Other Hospital/Academic/Medical Center)
Innovative Cellular Therapeutics Co.
Pancreatic Cancer; Pancreatic Neoplasms
Inici:
22/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1b, Multicenter, Open-Label Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Mezagitamab (TAK-079) in Patients With P...
Takeda
Glomerulonephritis, IGA; Kidney Diseases
Inici:
17/07/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
The Safety, Tolerability, and Pharmacokinetic Characteristics of DXC007 (Recombinant Humanized Anti-CD33 Monoclonal Antibody-Tub255 Conjugate) for Inj...
Hangzhou DAC Biotech Co.
Acute Myelocytic Leukemia; Chronic Lymphocytic Leukemia; Chronic Myeloid Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Double Blind, Randomized, Placebo-Controlled, Phase 1 Dose Escalation Trial to Evaluate the Safety and Immunogenicity of an Inactivated Yellow Fever...
National Institutes of Health/National Institute of Allergy and Infectious Diseases
Najit Technologies
Fever; Yellow Fever
Inici:
13/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Expanded Access Program for Pirtobrutinib for Previously Treated B-Cell Cancers
Eli Lilly/Loxo Oncology
Chronic Lymphocytic Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of Magrolimab in Children and Adults With Recurrent or Progressive Malignant Brain Tumors
Gilead Sciences
University of California, San Francisco
Brain Neoplasms; Glioblastoma; Neoplasms
Inici:
22/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open, Multicenter Phase Ib Clinical Study of F0002-ADC in Patients with Relapsed/Refractory CD30-Positive Peripheral T-cell Lymphoma
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical
Shanghai Pharmaceuticals Holding Co./Shanghai Jiaolian Drug Development Co.
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral
Inici:
29/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1 Combined Single and Multiple Ascending Oral Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP873...
Astellas Pharma/Astellas Pharma Global Development
Anemia, Sickle Cell; Sickle Cell Anemia; Sickle Cell Trait; Unspecified
Inici:
07/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I First-in-Human, Drug-dose Escalation Study of RM-1995 Photoimmunotherapy, as Monotherapy or Combined With Pembrolizumab, in Patients With Ad...
Rakuten Medical
Carcinoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck
Inici:
24/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase 1 clinical trial to evaluate the pharmacokinetic (PK) profile, efficacy and safety of Amikacin Cyclops
Groningen University Hospital
PureIMS
Tuberculosis
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, First in Human, Dose-Escalation Study of TORL-2-307-MAB in Participants With Advanced Cancer
(Other Academic Cancer Center)
TORL Biotherapeutics
Esophageal Cancer; Esophageal Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
20/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A phase I Clinical Study of SIM1811-03 injection intended to treat advanced solid tumors and skin T-cell lymphoma
Simcere Pharmaceutical Group {Jiangsu Simcere Pharmaceutical Co.}
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms, Unknown Primary
Inici:
16/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A randomized, double-blind, placebo-controlled, multiple-dose escalation clinical study to evaluate the safety, tolerability and pharmacokinetic chara...
Chongqing Dikang Changjiang Pharmaceutical Co.
Hypertension; Hypertension, Pulmonary
Inici:
23/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II, Open-Label, Multicenter, Randomized Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients Wi...
Roche {F. Hoffmann-La Roche}
Roche/Genentech
Carcinoma; Esophageal Cancer; Esophageal Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
23/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II Open Label Dose Confirmation, Proof of Concept Study of Siremadlin in Combination With Venetoclax Plus Azacitidine in Unfit Adult AML Pa...
Novartis
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
10/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of Safety, Tolerability and Pharmacokinetics of T-1301 Capsules in Subjects With Advanced Solid Tumors
Taivex Therapeutics
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Unknown Primary
Inici:
19/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1/2a Study of the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Subcutaneously Administered CDK-003 in Healthy Adult Particip...
Codiak BioSciences
Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous
Inici:
09/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, First in Human, Dose-Escalation Study of TORL-2-307-ADC in Participants With Advanced Cancer
Organisation for Oncology and Translational Research
TORL Biotherapeutics
Esophageal Cancer; Esophageal Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
02/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II, Open-Label Study To Evaluate The Safety, Pharmacokinetics, Pharmacodynamics, And Efficacy Of Elranatamab (PF-06863135) In Chinese Parti...
Pfizer
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
21/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single-arm, Open phase II Clinical study of Albumin Paclitaxel combined with Anlotinib in the treatment of Platinum-resistant Relapsed Ovarian Cance...
(Other Hospital/Academic/Medical Center)
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co.
Jiangsu Hengrui Pharmaceuticals Co.
Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms
Inici:
10/10/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I study of ITK inhibitors in the treatment of Relapsed and Refractory T-cell Lymphoma
Corvus Pharmaceuticals
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral
Inici:
03/05/2019
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label, Phase I Clinical Study to Evaluate the Safety, Tolerability, PK/PD and Preliminary Efficacy of HBM4003 in Combination With Toripalimab ...
Harbour BioMed Therapeutics/Harbour BioMed (Guangzhou) Co.
Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms; Neoplasms; Neoplasms, Unknown Primary
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label, Multicenter, Dose Escalation Study of PRT2527 in Patients With Advanced Solid Tumors
Prelude Therapeutics
Breast Neoplasms; Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Neoplasms; Neoplasms, Unknown Primary; Prostatic Neoplasms; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma; Triple Negative Breast Neoplasms
Inici:
14/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Observational Long-term Safety and Efficacy Follow-up Study After Ex-vivo Gene Therapy With BIVV003 in Participants With Severe Sickle Cell Disease...
Sanofi/Bioverativ
Anemia, Sickle Cell; beta-Thalassemia; Beta-Thalassemia; Lymphatic Diseases; Sickle Cell Anemia; Sickle Cell Trait; Thalassemia
Inici:
21/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1 Study of SPI-62+Prednisolone for the Treatment of Polymyalgia Rheumatica
Sparrow Pharmaceuticals
Polymyalgia Rheumatica
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multicenter, Open-label, Phase I Study Evaluating the Safety and Tolerability of HMPL-760 in Patients With Previously Treated Chronic Lymphocytic Le...
Hutchmed {Hutchison MediPharma}
Chronic Lymphocytic Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldens??????????????????????
Inici:
15/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1, Randomized, Placebo-controlled, Double-blind, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmac...
Neuracle Science
Alzheimer Disease; Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis; Motor Neuron Disease; Neurodegenerative Diseases; Parkinson Disease
Inici:
04/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of BEY1107G in Patients with Glioblastoma
BeyondBio Inc.
Glioblastoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Dose-Finding Clinical Trial With Expansion Cohort Evaluating CC-486 in Patients With Relapsed/Refractory T-Cell Large Granular Lymphocytic L...
Bristol-Myers Squibb
Chronic Lymphocytic Leukemia; Leukemia; Leukemia, Large Granular Lymphocytic; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Myelodysplastic Syndromes
Inici:
25/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Dose Finding Study Assessing Safety and Activity of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Extensive Stage Small Cell Lung Cancer (ES-SCLC)...
Novartis
Carcinoma, Small Cell; Lung Neoplasms; Neuroendocrine Tumors; Small Cell Lung Carcinoma
Inici:
30/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Study Of The Combination Of CD47 Blockade With SIRP-Alpha FC Fusion Proteins (TTI-622) And Daratumumab Hyaluronidase-fihj For Patients With...
Memorial Sloan-Kettering Cancer Center
Pfizer {Trillium Therapeutics {Stem Cell Therapeutics/Trillium Therapeutics}}
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
28/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label Phase I Clinical Study To Evaluate The Safety, Tolerability,Pharmacokinetics And Preliminary Efficacy Of HH-101 Injection As A Monothera...
Huahui Health
Bile Duct Neoplasms; Carcinoma, Non-Small-Cell Lung; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal Cancer; Esophageal Neoplasms; Melanoma; Stomach Carcinoma; Stomach Neoplasms
Inici:
19/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study on the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effects of CX1440 Capsules on the Pharmacokinetics o...
Hangzhou Aojin Biomedical Technology Co.
Chronic Lymphocytic Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
18/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single-Arm, Multi-Center Phase I/IIa Clinical Study To Evaluate The Safety, Tolerability, Biodistribution Characteristics And Biological Effects Of ...
Shanghai Pharmaceuticals Holding Co.
Immvira Co.
Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Hodgkin Disease; Hodgkin Lymphoma; Liver Cancer; Liver Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Mesothelioma; Neoplasms, Mesothelial; Neoplasms, Unknown Primary
Inici:
21/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase 1, Dose-Escalating, Double-Blind, Randomized, Comparator-Controlled Trial of the Safety, Tolerability, and Immunogenicity of the Transmission-Bl...
National Institutes of Health/National Institute of Allergy and Infectious Diseases
(Other Hospital/Academic/Medical Center)
Novavax
Malaria; Malaria, Falciparum; Rabies; Virus Diseases
Inici:
22/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Recombinant Humanized Anti-PCSK9 Monoclona...
Shanghai Junshi Biosciences Co.
Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Cancer; Liver Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Renal Cancer; Urethral Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor
Inici:
23/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Trial to Assess Safety, Tolerability and Anti-tumor Activity of Autologous T Cell Modified Chimeric Antigen Receptor (CAR) (CCT301-38) in Pa...
(Other Hospital/Academic/Medical Center)
Shanghai PerHum Therapeutics Co. {Shanghai Sinobioway Sunterra Biotechnology Co.} (Sinobioway Group, Sunterra Capital and F1 Oncology joint venture)
Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
30/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study Of TAS-116 (Pimitespib) In Combination With Imatinib In Patients With Advanced Gastrointestinal Stromal Tumor (GIST) (CHAPTER-GIST-101...
Otsuka Holdings/Taiho Pharmaceutical
Gastrointestinal Stromal Tumors
Inici:
01/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study to Evaluate the Safety and Clinical Activity of Allogeneic CAR-T Targeting CD7 in Patients With Refractory or Relapsed T Cell Malignancies
(Other Hospital/Academic/Medical Center)
Fundamenta Therapeutics
Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Inici:
22/01/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Trial of Maintenance Fedratinib to Prevent Post-Transplant Relapse in Myeloproliferative Neoplasms
Bristol-Myers Squibb
H. Lee Moffitt Cancer Center and Research Institute
Myeloproliferative Disorders; Neoplasms; Polycythemia Vera; Thrombocythemia, Essential
Inici:
14/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I clinical study to evaluate the safety and tolerability, pharmacokinetics and preliminary efficacy of humanized Claudin18.2 monoclonal antibody...
Zhejiang Doer Biologics Corporation
Esophageal Neoplasms; Neoplasms, Unknown Primary; Pancreatic Neoplasms; Stomach Neoplasms
Inici:
19/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Safety and Efficacy Evaluation of IM83 CAR-T Cells for Patients Wirh Advanced Liver Tumors
Beijing Immunochina Medical Science & Technology Co.
Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
24/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1/2 Open-Label, Dose-Escalation Study to Determine the Safety Tolerability & Efficacy of BMN 331 an AAV Vector-Mediated Gene Transfer of Human...
BioMarin
Angioedema; Angioedemas, Hereditary
Inici:
15/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase IB/IIA Trial Of CEND-1 In Combination With Neoadjuvant FOLFIRINOX Based Therapies In Pancreatic, Colon And Appendiceal Cancers (CENDIFOX)
University of Kansas
Cend Therapeutics
Colorectal Neoplasms; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Cancer; Pancreatic Neoplasms; Peritoneal Neoplasms
Inici:
16/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study to Evaluate the Safety, Tolerance and Efficacy of CRTE7A2-01 TCR-T Cell for HPV16 Positive Advanced Cervical, Anal, or Head and Neck C...
Corregene Biotechnology Co.
Anus Neoplasms; Head and Neck Neoplasms; Uterine Cervical Neoplasms
Inici:
28/06/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Mechanism of Resistance to GNC-038,a Tetra-specific T Cell Engager, in Relapsed and Refractory Diffuse Large B-cell Lymphoma
(Other Hospital/Academic/Medical Center)
Biokin Pharmaceutical/Sichuan Baili Pharmaceutical Co.
Lymphoma; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
25/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1 Open Label Study to Evaluate the Pharmacokinetics, Safety and Tolerability of ASP0367 in Participants With Renal Impairment Compared to Heal...
Astellas Pharma/Mitobridge
Muscular Dystrophies; Renal Insufficiency
Inici:
16/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Phase I Study To Evaluate The Safety, Tolerability, PK/PD And Preliminary Efficacy Of HBM4003 In Combination With Treprizumab In Patients With...
Harbour BioMed Therapeutics
Neoplasms; Neoplasms, Unknown Primary; Neuroendocrine Tumors
Inici:
04/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of IRF4rx in Patients with Multiple Myeloma
Flamingo Therapeutics
Multiple Myeloma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/IIa Study of Descartes-25 in Patients With Relapsed/Refractory Multiple Myeloma
Cartesian Therapeutics
Multiple Myeloma; Neoplasms, Plasma Cell; Recurrence
Inici:
25/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label, Dose Escalation of HBI-2376 in Patients With Advanced Malignant Solid Tumors Harboring KRAS or EGFR Mutations
HUYA Bioscience
Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Colorectal Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms
Inici:
13/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label Study of the Safety, Tolerability and Preliminary Clinical Activity of Allogeneic Invariant Natural Killer T (iNKT) Cells (agenT...
Agenus/MiNK Therapeutics
Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Liver Cancer; Liver Neoplasms; Multiple Myeloma; Neoplasms; Neoplasms, Unknown Primary
Inici:
28/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Dose Finding Study Assessing Safety and Activity of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Glioblastoma in Combination With Radiotherapy Wi...
Novartis
Glioblastoma
Inici:
10/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label, Multicenter, Dose Escalation Study of PRT1419 Injection in Patients With Relapsed/Refractory Hematologic Malignancies
Prelude Therapeutics
Acute Myelocytic Leukemia; Hematologic Neoplasms; Leukemia; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Myelodysplastic Syndromes; Myeloproliferative Disorders
Inici:
22/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label, Multi-Center, Phase I Study to Evaluate the Safety, Tolerability,Pharmacokinetic/Pharmacodynamics and Anti-tumor Activity of Tetra-spec...
Biokin Pharmaceutical/Sichuan Baili Pharmaceutical Co.
Biokin Pharmaceutical/SystImmune
Acute Myelocytic Leukemia; Chronic Lymphocytic Leukemia; Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lym?????
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, First in Human, Dose-Escalation Study of TORL-1-23 in Participants With Advanced Cancer
(Other Cooperative Group)
TORL Biotherapeutics
Carcinoma, Endometrioid; Endometrial Neoplasms; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms
Inici:
17/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
To Evaluate The Exploratory Clinical Study of all Human Anti-PD-L1 Antibody Injection (LDP) Combined With Recombinant Anti EGFR Human Mouse Chimeric M...
(Other Hospital/Academic/Medical Center)
Guilin Sanjin Pharmaceutical Co./Dragonboat Biopharmaceutical (Shanghai) Co.
Carcinoma, Endometrioid; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Cancer; Esophageal Neoplasms; Head and Neck Neoplasms; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms; Uterine Cervical Neoplasms
Inici:
01/02/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Label, Multicenter Phase Ib/II Clinical Study to Evaluate Efficacy , Safety and PK of HLX208 in Advanced Anaplastic Thyroid Cancer (ATC) With ...
Shanghai Henlius Biotech (Shanghai Fosun Pharmaceutical Co. and Henlius Biopharmaceuticals Co. joint venture)
Thyroid Carcinoma, Anaplastic; Thyroid Diseases; Thyroid Neoplasms
Inici:
10/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II Trial of Lurbinectedin Plus Doxorubicin in Leiomyosarcoma
Massachusetts General Hospital
Jazz Pharmaceuticals
Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
04/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Investigator-initiated Phase I Study of SELINEXOR in Combination With Bevacizumab and Atezolizumab in Newly Diagnosed Advanced Hepatocellular Carci...
H. Lee Moffitt Cancer Center and Research Institute
Karyopharm Therapeutics
Carcinoma; Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
03/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of Gentulizumab in Patients with Hematologic Malignancies, Advanced Malignant Solid Tumors and Lymphomas
GeneScience Pharmaceuticals Co.
Hematologic Neoplasms; Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms, Unknown Primary
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of JRF101c in Patients with Ovarian Cancer
Chengdu Jinrui Foundation Biotech Co.
Ovarian Cancer; Ovarian Neoplasms
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of JRF101b in Patients with Medulloblastoma
Chengdu Jinrui Foundation Biotech Co.
Medulloblastoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-tumor Activity of IPG7236 Administered Orally as a Single...
Immunophage Biotech Co.
Breast Neoplasms; Carcinoma, Renal Cell; Head and Neck Neoplasms; Kidney Neoplasms; Melanoma; Neoplasms, Unknown Primary; Renal Cancer; Unspecified; Wilms Tumor
Inici:
15/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1, 2-Part, Single Ascending Dose, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, a...
Lundbeck
Aprilbio
Neuromyelitis Optica; Unspecified
Inici:
18/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Immune Nephritis
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Autoimmune Diseases; Lupus Nephritis; Nephritis; Systemic Lupus Erythematosus
Inici:
20/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Sjogren''s Syndrome
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Autoimmune Diseases; Sjogren''s Syndrome; Syndrome
Inici:
05/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Scleroderma
(Other Hospital/Academic/Medical Center)
Yake Biotechnology
Autoimmune Diseases; Scleroderma, Diffuse; Scleroderma, Localized; Scleroderma, Systemic; Systemic Scleroderma
Inici:
08/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Trial of ProAgio, an Anti- avß3 Integrin Cytotoxin, for Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies
National Institutes of Health/National Cancer Institute
ProDa BioTech
Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms
Inici:
29/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study of Hydroxychloroquine and Chlorphenesin Carbamate in Combination With mFOLFIRINOX in Inoperable Locally Advanced or Metastatic Pancreatic Canc...
Asan Medical Center
CytoGen, Inc.
Oncocross
Pancreatic Cancer; Pancreatic Neoplasms
Inici:
30/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A phase 1 study of BIO 017 for Angelman Syndrome
Biom Therapeutics
Angelman Syndrome
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of XmAb968 in Patients with T-cell Acute Lymphoblastic Leukaemia (T-ALL), Acute Myeloid Leukaemia (AML), T-cell Lymphoblastic Lymphoma...
Xencor
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 0 ''Trigger'' Trial of Niraparib in Newly-diagnosed Glioblastoma and Recurrent IDH1/2(+) ATRX Mutant Glioma
GlaxoSmithKline
University of California, San Francisco
(Other Hospital/Academic/Medical Center)
Glioblastoma; Glioma
Inici:
29/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Study of MEM-288 Oncolytic Virus in Solid Tumors Including Non-Small Cell Lung Cancer (NSCLC)
H. Lee Moffitt Cancer Center and Research Institute
Duke Comprehensive Cancer Center
Memgen
Breast Neoplasms; Carcinoma; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Lung Neoplasms; Melanoma; Neuroendocrine Tumors; Pancreatic Cancer; Pancreatic Neoplasms; Triple Negative Breast Neopla???
Inici:
23/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Exploratory Study On The Treatment Of Hematological Malignancies With IMM01 For Injection
ImmuneOnco Biopharmaceuticals (Shanghai) Co.
Acute Myelocytic Leukemia; Hodgkin Disease; Hodgkin Lymphoma; Leukemia, Myeloid, Acute; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Multiple Myeloma; Myelodysplastic Syndromes
Inici:
18/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/IIa Open Label Multicenter, Non-Randomized, Trial to Assess the Safety and Efficacy of CYNK-001in Combination With Recombinant Human Interle...
Celularity
Astrocytoma; Glioblastoma
Inici:
08/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Open-label, Single Arm Study Targeting Glypican-3 (GPC3) Chimeric Antigen Receptor Modified T Cells (CAR-T) for Treatment of Advanced Hepato...
(Other Hospital/Academic/Medical Center)
Shanghai Pharmaceuticals Holding Co.
Carcinoma; Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
29/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Steady-State Bioequivalence Study Of Olaparib Tablets In Patients With Ovarian Cancer: Multi-Center, Postprandial, Random, Open, Two-Period, Two-Cross...
Sichuan Kelun Pharmaceutical Co.
Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms
Inici:
15/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Label Phase I PET Imaging Study to Investigate the Biodistribution and Tumor Uptake of [89Zr]Zr-BI 765063 in Patients With Head and Neck Squam...
Boehringer Ingelheim
Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Lung Neoplasms; Melanoma; Squamous Cell Carcinoma of Head and Neck
Inici:
16/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I trial of RG6315 for scleroderma
Roche
Systemic Scleroderma
Inici:
15/08/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Double-Blinded, Placebo-Controlled, MultipleAscending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodyn...
Sumitomo Dainippon Pharma/Sumitovant Biopharma/Altavant Sciences {Roivant Sciences/Altavant Sciences}
Hypertension; Hypertension, Pulmonary; Unspecified
Inici:
01/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Dose-Escalation Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of ACT001 In Patients With Advanced Solid Tumors (Part B).
Tianjin Accendatech Technology Co./Accendatech AU Pty
Glioblastoma
Inici:
15/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II, Closed Label, Randomized, Pilot Study for the Safety and Efficacy of TolaSure Gel, 5% w/w Targeting Aggregated Mutant Keratin in Severe ...
BioMendics
Epidermolysis Bullosa; Epidermolysis Bullosa Simplex
Inici:
02/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Clinical Trial evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SKB315 for Injection in Patients with Advance...
Sichuan Kelun Pharmaceutical Co./Sichuan Kelun Botai Biopharmaceutical Co.
Esophageal Cancer; Esophageal Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
16/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Trial of Human Chimeric Antigen Receptor Modified T Cells (huCART-meso) Administered in Combination With VCN-01 in Patients With Pancreatic an...
University of Pennsylvania
VCN Biosciences
Carcinoma, Ovarian Epithelial; Ovarian Cancer; Ovarian Neoplasms; Pancreatic Cancer; Pancreatic Neoplasms
Inici:
17/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I, Open-Label, Multicentre, Dose-Escalation Study to Evaluate the Safety and Pharmacokinetics of A Single Intravenous PPMX-T003 in Polycythemia ...
Perseus Proteomics Inc.
Myeloproliferative Disorders; Polycythemia; Polycythemia Vera
Inici:
01/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Pulmonary Gas Exchange and Neuro-sensory Abnormalities in Patients With Idiopathic Pulmonary Fibrosis and Mild Mechanical Restriction. Implications fo...
Boehringer Ingelheim
(Other Hospital/Academic/Medical Center)
Fibrosis; Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis
Inici:
21/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/II Trial of Radiotherapy in Combination With Atezolizumab Prior to Surgical Resection for HPV-unrelated Squamous Cell Carcinoma of the Head an...
National Institutes of Health/National Cancer Institute
University of Colorado
Roche/Genentech
Carcinoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck
Inici:
02/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Application of ctDNA Assay in the Neoadjuvant and Adjuvant Chemotherapy Setting in Patients With Resectable Pancreatic Cancer
University of Oklahoma
Natera
Pancreatic Cancer; Pancreatic Neoplasms
Inici:
25/05/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Dose Escalation Study of ZN-d5 Monotherapy in Chinese Subjects With Non-Hodgkin Lymphoma
Thermo Fisher Scientific/Patheon
Zentera Therapeutics/Zentera Therapeutics HK
Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
21/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/IIa clinical trial to evaluate the safety, tolerability, pharmacokinetic characteristics and preliminary efficacy of CDK9 inhibitor YK-2168 in...
Nanjing Yoko Pharmaceutical Group Co./Nanjing Yoko Bio-Medical Research Co.
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms, Unknown Primary
Inici:
19/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Trial of Anti-CD19 Universal CAR-T Therapy For Relapsed/Refractory Diffuse Large B-Cell Lymphoma
(Other Hospital/Academic/Medical Center)
Sunnycell Therapeutics
Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
01/03/2019
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Trial in Anti-BCMA CAR-T
The Pregene (Shen Zhen) Biotechnology Company
Multiple Myeloma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Long-Term Follow-up of Fabry Disease Subjects Who Were Treated With ST-920, an AAV2/6 Human Alpha Galactosidase A Gene Therapy
Sangamo Therapeutics/TxCell
Fabry Disease
Inici:
16/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A First-In-Human, Multicenter, Open-Label, Phase I Dose Escalation Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of YH004 As A Singl...
Biocytogen/Eucure (Beijing) Biopharma Co.
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms, Unknown Primary; Unspecified
Inici:
07/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Study to Evaluate the Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of MK-0482 in Participants With Relapsed or Refractory Ac...
Merck & Co./Merck Sharp & Dohme (MSD)
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
26/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label Multicenter Phase Ib Study of AN0025 in Combination With Chemoradiotherapy in Patients With Locally Advanced/Locally Recurrent Esophagea...
Adlai Nortye Biopharma Co.
Esophageal Cancer; Esophageal Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
23/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open, Single-Arm, Multi-Center Phase II Clinical Study To Evaluate The Efficacy And Safety Of Recombinant Anti-PD-1 Humanized Monoclonal Antibody I...
3SBio/Sunshine Guojian Pharmaceutical (Shanghai) Co.
Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
21/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Bioequivalence Study with the Improved Version of dasatinib at a Lower Dose Strength Compared with Sprycel in Patients with Acute Lymphoblastic Leuk...
Xspray
Chronic Myeloid Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single-arm, Multicenter, Phase Ib/II Clinical Study of Docetaxel for Injection (Albumin-bound) in Combination With Nivolumab in Patients With Recurr...
CSPC Pharmaceutical Group Co./CSPC ZhongQi Pharmaceutical Technology Co.
Carcinoma; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Squamous Cell Carcinoma of Head and Neck
Inici:
01/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Safety And Efficacy Of Radiotherapy Combined With CAR-T Immunotherapy For High-Risk Lymphoid Malignancies
(Other Hospital/Academic/Medical Center)
Hunan Siweikang Therapeutics Co.
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Multiple Myeloma
Inici:
11/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multi-center, Phase I, Open Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Efficacy of ...
Shandong Taize Huikang Biological Medicine Co.
Shandong TheraWisdom Biopharma Co.
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms; Neoplasms, Unknown Primary
Inici:
08/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of Vyxeos Plus Gilteritinib in Relapsed or Refractory, FLT3-Mutated Acute Myeloid Leukemia
H. Lee Moffitt Cancer Center and Research Institute
Jazz Pharmaceuticals
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
23/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multi-center, Phase Ib/IIa Clinical Trial to Evaluate the Tolerability, PK and Efficacy of ZSP1603 in Patients With Idiopathic Pulmonary Fibrosis
Guangdong Zhongsheng Pharmaceutical Co./Guangdong Raynovent Biotech Co.
Fibrosis; Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis
Inici:
12/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Double-blind, Placebo-controlled Study of the Safety, Tolerability, and Pharmacokinetics of Single Ascending Dosed of HSK31858 in Health...
Haisco Pharmaceutical Group Co.
Bronchiectasis; Unspecified
Inici:
28/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Pilot Study of the Safety and Efficacy of Anti-FLT3 Chimeric Antigen Receptor Engineered T-Cells in the Treatment of Relapsed or Refractory Acute Myel...
(Other Hospital/Academic/Medical Center)
PersonGen BioTherapeutics (Suzhou) Co.
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
19/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Study of AMAX-126 in Patients with Glioblastoma
Aveta Biomics
Glioblastoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A phase Ib Clinical Study Evaluating the safety, Pharmacokinetics and Preliminary Efficacy of QL1706 injection Combined with Bevacizumab injection in ...
Qilu Pharmaceutical Co.
Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
01/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
TAA05 Cell Injection in the Treatment of Recurrent / Refractory Acute Myeloid Leukemia
(Other Hospital/Academic/Medical Center)
PersonGen BioTherapeutics (Suzhou) Co.
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
01/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open Label, Multi-Center, Two-Treatment, Three Period, Three-Sequence, Reference Replicate, Multiple Dose, Steady-State, Bioequivalence ...
Natco Pharma
Breast Neoplasms; Fallopian Tube Neoplasms; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms
Inici:
16/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of Venetoclax in Combination With Inotuzumab Ozogamicin for B-cell Acute Lymphoblastic Leukemia (B-ALL)
Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
AbbVie
Chronic Myeloid Leukemia; Leukemia; Leukemia, Lymphoid; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Lymphoma, B-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
24/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multicentric Open Label Randomized Two Period Two Treatment Two Sequence Crossover Multiple Dose Steady State Bioequivalence Study Of Sunitinib Mala...
Eugia Pharma Specialities (Aurobindo Pharma and Celon Laboratories joint venture)
Carcinoma, Renal Cell; Kidney Neoplasms; Renal Cancer; Wilms Tumor
Inici:
15/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study Evaluating the Safety, Tolerability, And Pharmacokinetics of IMGN853 in Chinese Adult Patients with Folate Receptor 1 (FOLR1) Positive...
ImmunoGen
Huadong Medicine Co./Hangzhou Zhongmei Huadong Pharmaceutical Co.
Almac Group/Almac Clinical Services
BSP Pharmaceuticals
Carcinoma, Endometrioid; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms; Peritoneal Neoplasms
Inici:
22/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase Ib Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis (Neurofibromatosis an...
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co.
Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Nerve Sheath Neoplasms; Neurofibroma; Neurofibromatoses; Neurofibromatosis 1; Neurofibrosarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
31/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Study to Evaluate the Safety and Effectiveness of Anti-BCMA CAR-NK Therapy in Relapsed or Refractory Multiple Myeloma
Sichuan Kelun Pharmaceutical Co.
Xinqiao Hospital of Chongqing
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
01/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Study to Evaluate the Safety and Effectiveness of Anti-CD33 CAR NK Cell Therapy in Relapsed/Refractory Acute Myeloid Leukemia
Sichuan Kelun Pharmaceutical Co.
Xinqiao Hospital of Chongqing
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
23/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II,Multi-center, Open, Multiple-dose Design to Evaluate the Safety,Tolerability and Efficacy of STSP-0601 for Injection in Patients With In...
Staidson (Beijing) Biopharmaceuticals Co.
Blood Coagulation Disorders; Hemophilia A; Hemophilia B; Hemostatic Disorders
Inici:
18/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study of Chemotherapy Combined With Camrelizumab and Apatinib in First-line Treatment of Extensive Stage Small Cell Lung Cancer
(Other Hospital/Academic/Medical Center)
Jiangsu Hengrui Pharmaceuticals Co.
Carcinoma, Small Cell; Lung Neoplasms; Neuroendocrine Tumors; Small Cell Lung Carcinoma
Inici:
27/01/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Novel Combination of Belantamab Mafodotin and Elotuzumab to Enhance Therapeutic Efficacy in Multiple Myeloma
GlaxoSmithKline
Yale University
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
21/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open, Two-cycle, Two-Crossover Bioequivalence Pilot Study of Irinotecan Hydrochloride Liposomal Injection (43mg/10mL) in Patients With A...
Zhejiang Shenzhou Pharmaceutical Co.
Pancreatic Cancer; Pancreatic Neoplasms
Inici:
02/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Initial Efficacy of Recombinant Humanized Anti-BTLA Monoclonal Antibody ...
Shanghai Junshi Biosciences Co.
Suzhou Zhonghe Biopharmaceutical
Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Lung Neoplasms; Neuroendocrine Tumors; Small Cell Lung Carcinoma
Inici:
27/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Phase Ib, Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Maximum Tolerated or Administered Dose, Pharmacokin...
Bayer AG
Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Head and Neck Neoplasms; Kidney Neoplasms; Neoplasms, Unknown Primary; Renal Cancer; Unspecified; Urethral Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor
Inici:
30/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Open-Label Study of Genetically Engineered Oncolytic HSV-1 (C5252) Expressing IL-12 and Anti-PD-1 Antibody in Patients With Recurrent or Pro...
Immvira Co.
Glioblastoma; Neoplasms, Unknown Primary
Inici:
21/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Multi-center Phase Ib/II Study to Evaluate the Tolerance and Efficacy of Mitoxantrone Hydrochloride Liposome Injection Combined With Cy...
CSPC Pharmaceutical Group Co./CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co.
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute
Inici:
08/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study Evaluating the Safety, Tolerability, and Pharmacokinetics of LUCAR-20S in Patients With Relapsed/Refractory Diffuse Large B-Cell, Follicular, ...
(Other Hospital/Academic/Medical Center)
Nanjing Legend Biotechnology Co.
Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
01/12/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I clinical trial evaluating HD CD19 CAR-T treatments for invasive B-cell non-Hodgkin''s lymphoma patients that are difficult to treat or relap...
Huadao (Shanghai) Biopharma Co.
Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
24/08/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Pharmacokinetic and Pharmacodynamic Study of AMX0035 in Patients With ALS
Amylyx Pharmaceuticals
Amyotrophic lateral sclerosis; Amyotrophic Lateral Sclerosis; Motor Neuron Disease; Unspecified
Inici:
05/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase IB/II of CPX-351 as Maintenance Therapy in AML Patients Ineligible for Bone Marrow Transplantation
National Institutes of Health/National Heart, Lung, and Blood Institute
Jazz Pharmaceuticals
Georgetown University
Acute Myelocytic Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
08/02/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Dose Escalation And Dose Expansion Study Of The Safety, Tolerability, Pharmacokinetic Characteristics And Preliminary Anti-Tumor Activity Of W...
Cisen Pharmaceutical Co.
Breast Neoplasms; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms
Inici:
07/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Study of Oral Decitabine/Cedazuridine as Maintenance Therapy Following Allogeneic Hematopoietic Cell Transplantation for Patients With Myel...
Otsuka Holdings/Taiho Pharmaceutical
Massachusetts General Hospital
Leukemia; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Juvenile; Myelodysplastic Syndromes; Neoplasms; Preleukemia
Inici:
17/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I Clinical Study of Safety & Efficacy of DC Vaccine and TMZ for the Treatment of Newly-diagnosed Glioblastoma After Surgery
(Other Hospital/Academic/Medical Center)
Guangdong Zhongsheng Pharmaceutical Co.
Glioblastoma
Inici:
30/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Prospective, Open, Dose-escalation, Multi-center, Phase 1/2a Trial to Evaluate the Safety, Tolerability and to Explore the Efficacy of PN-101 in Pat...
Paean Biotechnology
Dermatomyositis; Dermatomyositis; Polymyositis
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase Ib/II Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
Cedars-Sinai Medical Center
Merck & Co./Merck Sharp & Dohme (MSD)
Glioblastoma
Inici:
09/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
To Evaluate the Safety and Efficacy of LY011 Cell Injection (Targeting CLDN 18.2 Chimeric Antigen Receptor T Cells) in the Treatment of Advanced Gastr...
(Other Hospital/Academic/Medical Center)
Shanghai Longyao Biotechnology
Adenocarcinoma; Esophageal Cancer; Esophageal Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
26/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Open-Label, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of ADCT...
Auven Therapeutics/ADC Therapeutics
Bile Duct Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Cholangiocarcinoma; Fallopian Tube Neoplasms; Kidney Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Neuroendocrine Tumors; Ovarian Cancer; Ovarian Neoplasms; Prostatic Neoplasms; Renal Cance??????????????
Inici:
09/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Multicenter Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-T2C CAR-T Cells in Relapsed or Refractory CD4+ T Lymphocyte Tu...
(Other Hospital/Academic/Medical Center)
Nanjing Legend Biotechnology Co.
Leukemia, T-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
15/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label, Dose Escalation/Dose Exploration, Phase I Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single/Multiple Infusion o...
(Other Hospital/Academic/Medical Center)
CARsgen Therapeutics
Carcinoma; Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
05/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma
Da Zen Theranostics
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms, Unknown Primary; Pancreatic Cancer; Pancreatic Neoplasms; Prostatic Neoplasms
Inici:
12/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib/II Single-arm Study Evaluating the Safety and Efficacy of Combined Immunotherapy With mFOLFOX6, Bevacizumab and Atezolizumab in Advanced-st...
(Other Hospital/Academic/Medical Center)
Roche {F. Hoffmann-La Roche}
Bile Duct Neoplasms; Biliary Tract Neoplasms; Cholangiocarcinoma
Inici:
01/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Clinical Trial of a 3-dose, 28-Day Regimen of PfSPZ Vaccine in Healthy, Malaria-Naïve, Adult Subjects to Determine Safety, Tolerability and Efficacy...
Fred Hutchinson Cancer Research Center
Sanaria
Malaria
Inici:
27/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study of CLDN18.2 Chimeric Antigen Receptor T Cells in the Treatment of Advanced Pancreatic Cancer
Shanghai Longyao Biotechnology
Pancreatic Cancer; Pancreatic Neoplasms
Inici:
19/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
RENEW: Pilot Study of Feasibility of CMV RNA-Pulsed Dendritic Cells Vaccines for the Treatment of Newly Diagnosed Glioblastoma Patients.
University of Florida - Gainesville
Immunomic Therapeutics
Glioblastoma
Inici:
30/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of Uproleselan Combined With Azacitidine and Venetoclax for the Treatment of Older or Unfit Patients With Treatment Naive Acute Myeloi...
National Institutes of Health/National Cancer Institute
GlycoMimetics
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
02/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open, Dose-Escalated Phase I Clinical Trial To Evaluate The Safety Of YS-ON-001 In Subjects With Advanced Breast Cancer, Advanced Lung Cancer, Adva...
YiSheng Biopharma
Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Cancer; Liver Neoplasms; Melanoma
Inici:
31/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ia Clinical Study to Evaluate Safety,Tolerability, Pharmacokinetics and Pharmacodynamics of Recombinant Anti-CD20 Humanized Monoclonal Antibod...
Shanghai Pharmaceuticals Holding Co.
Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia
Inici:
16/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of Mitoxantrone Hydrochloride Liposome Injection in Combination With Bortezomib and Dexamethasone in Patients With Relapsed o...
CSPC Pharmaceutical Group Co./CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co.
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
20/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase IB/llA, Open-label Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Fosciclopirox Alone and In Combination With Cytarabine in Pa...
CicloMed
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
27/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib, Open-label, Parallel Group, Multiple-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Oral Decitabine and Cedazuri...
Otsuka Holdings/Otsuka Pharmaceutical/Astex Pharmaceuticals
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms, Unknown Primary
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib, Open-label, Parallel Group, Multiple-dose Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Oral Decitabine and Cedazuri...
Otsuka Holdings/Otsuka Pharmaceutical/Astex Pharmaceuticals {SuperGen}
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Neoplasms, Unknown Primary
Inici:
25/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Intratumor CpG-ODN Boosters Immune Killing Against in Situ Tumor Antigen Released by Interventional Approaches for Advanced Solid Tumors
(Other Hospital/Academic/Medical Center)
Guangdong Zhaotai InVivo Biomedicine Co.
Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Cancer; Liver Neoplasms; Neoplasms, Unknown Primary
Inici:
01/03/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Clinical Study of TQB3820 tablets for the Treatment of Patients with Malignant hematological tumor
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co.
Chronic Lymphocytic Leukemia; Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms
Inici:
25/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study of Intratumoral Injection of CAR-T Cells in the Treatment of Advanced Liver Tumors
Beijing Immunochina Medical Science & Technology Co.
Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cholangiocarcinoma; Liver Cancer; Liver Neoplasms
Inici:
01/01/2019
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Effectiveness of MRX2843 Tablets in Patients With Relapsed/Refrac...
Betta Pharmaceuticals Co.
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
27/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
ONO-7913-02: Multi-Center, Open-Label Phase I Study of ONO-7913 (Magrolimab) in Combination With Azacitidine in Patients With MDS
Ono Pharmaceutical
Myelodysplastic Syndromes
Inici:
22/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Personalized Vaccine for Patients With Recurrent Malignant Glioma: a Single-arm, Single-center, Open-labeled Study
(Other Hospital/Academic/Medical Center)
Beijing Neoantigen Biotechnology Co.
Glioblastoma; Glioma
Inici:
29/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single Arm, Open-label, Multicenter, Phase Ib Study of TQ05105 Tablets in Subjects With aGVHD
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co./Nanjing Shunxin Pharmaceutical Co.
Graft Rejection; Graft vs Host Disease; Stem Cell Transplantation; Unspecified
Inici:
28/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multicenter Phase I, Open-Label Study of NB003 to Assess Safety, Tolerability, Pharmacokinetics and Efficacy in Patients With Advanced Malignancies
Ningbo NewBay Medical Technology Co.
Gastrointestinal Stromal Tumors; Neoplasms; Neoplasms, Unknown Primary
Inici:
06/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Non-gene Edited Anti-CD7 CAR T Cells for Relapsed/Refractory T Cell Malignances
(Other Hospital/Academic/Medical Center)
iCell Gene Therapeutics/iCAR Bio Therapeutics
Leukemia, Lymphoid; Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Inici:
01/12/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study Evaluating The Safety, Pharmacokinetics And Anti-Tumor Activity Of NKD0901In Patients With EGFR-Positive Advanced Solid Tumor
(Other Hospital/Academic/Medical Center)
Xiamen Nuokang Biotechnology Co.
Glioblastoma; Neoplasms, Unknown Primary
Inici:
01/09/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label, Single-Arm, Multi-Center Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of SHR-A1904 in Pa...
Jiangsu Hengrui Pharmaceuticals Co. {Jiangsu Hengrui Medicine}/Shanghai Hengrui Pharmaceutical {Shanghai Hengrui Pharmaceutical (Jiangsu Hengrui Medicine, HKG Science & Tech. JV)}
Pancreatic Cancer; Pancreatic Neoplasms
Inici:
06/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multi-Center Phase I Study of Codrituzumab in Pediatric Patients With Relapsed or Refractory Glypican 3 (GPC3) Expressing Extra-cranial Solid Tumors...
Memorial Sloan-Kettering Cancer Center
Roche/Chugai Pharmaceutical
Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms; Neoplasms; Neoplasms, Unknown Primary; Neuroblastoma
Inici:
09/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Novel Use of Restasis (Cyclosporine Ophthalmic Emulsion 0.05%) on Application of PROSE Devices for Management of Patients With Ocular Surface Disease:...
(Other Hospital/Academic/Medical Center)
AbbVie/Allergan {Allergan/Actavis {Actavis/Allergan}}
Dry Eye Syndromes; Graft Rejection; Graft vs Host Disease; Sjogren''s Syndrome; Unspecified
Inici:
15/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single Group, Open-Label, Multicenter ,Phase ?b/? Clinical Trials of TQ05105 Tablet in Patients With Glucocorticoid Refractory and Dependent Moderat...
Sino Biopharmaceutical/Chia Tai Tianqing Pharmaceutical Group Co./Nanjing Shunxin Pharmaceutical Co.
Graft Rejection; Graft vs Host Disease
Inici:
21/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Open-label Study of KPT-9274 in Patients With Relapsed and Refractory Acute Myeloid Leukemia
University of Colorado
Karyopharm Therapeutics
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
27/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Study to Investigate the Efficacy and Safety of MS-553 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphoc...
Shenzhen MingSight-Relin Pharmaceutical Co. (MingSight Pharmaceuticals and Shenzhen Relin Medicine joint venture)
Chronic Lymphocytic Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
28/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Open-Label Dose Escalation and Expansion Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of ...
Guangzhou Lupeng Pharmaceutical Co.
Lymphoma; Lymphoma, B-Cell; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Waldenstrom Macroglobulinemia
Inici:
06/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib Study of Isatuximab, Velcade, and Dexamethasone in Patients With Multiple Myeloma and Severe KIDNEY Disease
Washington University School of Medicine
Sanofi
Kidney Diseases; Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
01/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Studiy of Safety and Preliminary Efficacy of EBV CAR T Cells in Patients with Relapsed/Refractory EBV Positive Lympohma
(Other Hospital/Academic/Medical Center)
Guangzhou Bairui Biomedical Technology Co.
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Peripheral
Inici:
31/05/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Combination Study of NMS-03305293 and Temozolomide in Adult Patients With Recurrent Glioblastoma
Nerviano Medical Sciences
Glioblastoma
Inici:
01/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Single Arm, Open Label, Phase 1b/2 Study of Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD
Ohio State University
Daiichi Sankyo/Plexxikon
Graft Rejection; Graft vs Host Disease
Inici:
24/03/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical trial of human umbilical cord-derived mesenchymal stem cells in the treatment of refractory acute hematopoietic stem cell transplantation and...
Tianjin Amcellgene Engineering Co.
Graft Rejection; Graft vs Host Disease
Inici:
31/12/2020
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I clinical trial to evaluate the safety of freeze-dried human rabies vaccine (Vero cells) in Chinese healthy people aged 10 to 60
Guangzhou Realbenefitspot Pharmaceutical Co.
Guangzhou Yinhe Yangguang Biological Products Co.
Rabies; Virus Diseases
Inici:
09/05/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Study to Evaluate the Tolerance, Safety, Pharmacokinetics and Preliminary Efficacy of HER2-targeted CAB-T (PM3002) in Patients with Advanced Solid T...
(Other Hospital/Academic/Medical Center)
Hainan Kaibo Biological Technology Co.
Breast Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Neoplasms, Unknown Primary; Renal Cancer; Stomach Carcinoma; Stomach Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor
Inici:
07/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Clinical Study of JS004, a Recombinant Humanized mAb Specific to B-and T-Lymphocyte Attenuator (BTLA), in Subjects With Head and Neck Can...
Shanghai Junshi Biosciences Co./TopAlliance Biosciences
Head and Neck Neoplasms; Nasopharyngeal Carcinoma
Inici:
12/05/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase Ib, Multi-center, Open-label Dose Escalation and Expansion Platform Study of VAY736 as Single Agent and in Combination With Select Antineoplas...
Novartis
Lymphoma; Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
10/10/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Trial of AK117 (Anti-CD47) in Patients With Higher-risk Myelodysplastic Syndrome
Akeso Biopharma
Myelodysplastic Syndromes; Preleukemia; Syndrome
Inici:
18/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multicenter, Open-label, Phase Ib Study of Mitoxantrone Hydrochloride Liposome Injection in Subjects With Advanced Bone and Soft Tissue Sarcoma Who ...
CSPC Pharmaceutical Group Co./CSPC ZhongQi Pharmaceutical Technology Co.
Ewing Sarcoma; Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
29/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-Label Pilot Study to Evaluate the Safety and Efficacy of DVX201 NK Cells in Patients With Relapsed or Refractory AML or High Risk MDS or High ...
(Other Hospital/Academic/Medical Center)
Deverra Therapeutics
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Myeloproliferative Disorders; Unspecified
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A First-in-human, Open-label, Multiple Center Phase I Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetic, Immunogenicity, and Pre...
Lunan Pharmaceutical Group Corporation/Shandong New Time Pharmaceutical Co.
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
30/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I and Expansion Cohort Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractor...
(Other Cooperative Group)
St. Jude Children''s Research Hospital
AbbVie
Karyopharm Therapeutics
Acute Disease; Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence
Inici:
15/11/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
DNV3 Injection Open and Multi-Site Phase I/IIa Clinical Trial Of Safety, Tolerance, Pharmacokinetics and Preliminary Efficacy in Patients with Advance...
Chinese Academy of Medical Sciences
Zhejiang Shimai Pharmaceutical Co.
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms, Unknown Primary
Inici:
17/05/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase IB Study of Safety, Efficacy and Pharmacokinetic of Intravenously Administered Pelcitoclax (APG-1252) in Patients With Advanced Neuroendocrine...
Ascentage Pharma Group
Neuroendocrine Tumors
Inici:
21/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open, Single-arm, Multi-center Phase I Clinical Study of Recombinant Human Thrombopoietin Mimetic Peptide-Fc Fusion Protein for Injection in the Tr...
Sino Biopharmaceutical/Beijing Tide Pharmaceutical Co.
Purpura, Thrombocytopenic, Idiopathic
Inici:
19/06/2019
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of CT-2426 in Patients with Myelodysplastic syndrome, Glioma
Shouyao Holdings (Beijing) Co.
Glioblastoma; Myelodysplastic Syndromes
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Open-label, Multi-center Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics/Pharmacodynamics and Efficacy of BR790 Monotherapy in ...
Qingfeng Pharmaceutical Group Co./Jiangxi Qingfeng Pharmaceutical Co.
Carcinoma, Non-Small-Cell Lung; Esophageal Cancer; Esophageal Neoplasms; Head and Neck Neoplasms; Neoplasms; Neoplasms, Unknown Primary
Inici:
28/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of JAB-8263 in Patients with Myelofibrosis (MF) and Acute Myeloid Leukemia (AML)
Beijing Jacobio Pharmaceuticals Co.
Acute Myelocytic Leukemia; Leukemia, Myeloid, Acute; Myeloproliferative Disorders; Primary Myelofibrosis
Inici:
01/03/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase IB, Open-label, Global, Multicenter, Dose Determination Study to Evaluate Safety, Tolerability, and Preliminary Efficacy of CC-486 (ONUREG®) i...
Bristol-Myers Squibb/Celgene
AbbVie
Acute Myelocytic Leukemia; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute
Inici:
01/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Open-label, Dose Escalation Study to Investigate the Safety, Pharmacokinetics, Pharmacodynamics, and Clinical Activity of the FHND6091 in Su...
Jiangsu Chia Tai Fenghai Pharmaceutical Co. (CP Pharmaceutical Group and Jiangsu Provincial Agricultural Reclamation and Development Co., Ltd. joint venture)
Multiple Myeloma; Neoplasms, Plasma Cell
Inici:
22/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Study Evaluating the Safety and the Efficacy of SMART101 Injection to Accelerate Immune Reconstitution After T Cell Depleted Allogeneic H...
Smart Immune
Acute Myelocytic Leukemia; Graft Rejection; Graft vs Host Disease; Leukemia; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
09/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Multi-Center, Open, Non-Randomized, Dose-Escalating Clinical Trial Of Intratumoral Administration Of Clostridium Gordonii Spores Freeze-Drie...
Shandong Xinchuang Biotechnology Co.
Ewing Sarcoma; Fibrosarcoma; Leiomyosarcoma; Liposarcoma; Melanoma; Neoplasms, Unknown Primary; Osteosarcoma; Rhabdomyosarcoma; Sarcoma; Soft Tissue Neoplasms; Soft Tissue Sarcoma; Synovial Sarcoma
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open-label, Multi-centre, Phase I/II Study to Investigate the Safety, Tolerability, and Preliminary Efficacy of CN1 in Combination With CN401 in Ad...
Curon Biopharmaceutical/Curon Biopharmaceutical (Australia)
Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms
Inici:
28/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multi-center, Phase Ia/Ib, Open Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetics of TWP-101 in Patients With Advanced Melano...
Shandong TheraWisdom Biopharma Co.
Carcinoma; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Kidney Neoplasms; Melanoma; Renal Cancer; Urethral Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor
Inici:
07/02/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
An Open Label Evaluation Phase I Trial of the Safety and Pharmacokinetics of MRX-2843 in Adolescents and Adults With Relapsed/Refractory Acute Myeloid...
Meryx
Acute Myelocytic Leukemia; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma
Inici:
12/04/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of SYHA1817 in Patients with Gastric Carcinoma, Cancer of Biliary Duct, Squamous Cell Lung Carcinoma
CSPC Pharmaceutical Group Co.
Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Cancer; Liver Neoplasms; Stomach Carcinoma; Stomach Neoplasms
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Clinical Study Of XNW5004 Tablets In Assessing Safety, Tolerability, Pharmacokinetics, Pharmacodynamics And Preliminary Efficacy In Patients With Rela...
Sinovent
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin; Neoplasms, Unknown Primary
Inici:
27/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Non-Randomized, Open-Label, Adaptive, Single Center, Positron Emission Tomography (Pet) Study To Assess Distribution Of RO7248824 In The Central Ner...
Roche {F. Hoffmann-La Roche}
Angelman Syndrome
Inici:
29/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/II Study of Ipilimumab Plus Nivolumab (IPI-NIVO) Combined With Sacituzumab Govitecan (SG) as First-line Treatment for Cisplatin-ineligible Met...
Bristol-Myers Squibb
H. Lee Moffitt Cancer Center and Research Institute
Gilead Sciences
Carcinoma; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Kidney Neoplasms; Renal Cancer; Urethral Neoplasms; Urinary Bladder Neoplasms; Wilms Tumor
Inici:
30/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I, Multicenter, Open-label, Dose Finding Study of CC-96673 in Subjects With Relapsed or Refractory Non-Hodgkin''s Lymphoma
Bristol-Myers Squibb/Celgene
Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
20/01/2022
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Pilot Study of Neoadjuvant Stereotactic Beam Radiation Therapy Followed by Atezolizumab and Bevacizumab in Resectable Hepatocellular Carcinoma
Massachusetts General Hospital
Roche/Genentech
Carcinoma; Carcinoma, Hepatocellular; Liver Cancer; Liver Neoplasms
Inici:
18/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open Label, Multi-Center, Two-Treatment, Two-Period, Two-Sequence, Two-Way Cross-Over, Multiple Dose, Steady-State Relative Bioavailabil...
Oncogen Pharma (Malaysia)
Carcinoma, Renal Cell; Kidney Neoplasms; Renal Cancer; Wilms Tumor
Inici:
08/04/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II Study of Acalabrutinib, Venetoclax, and Obinutuzumab in Patients With Relapsed/Refractory and Previously Untreated Mantle Cell Lymphoma
AstraZeneca
Roche/Genentech
Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
02/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Phase I/II, Multicenter, First-In-Human, Dose Escalation and Dose Expansion Study of CPO107 Administered Intravenously to Patients With Advanced CD20-...
CSPC Pharmaceutical Group Co./Conjupro Biotherapeutics
Chronic Lymphocytic Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Mantle-Cell; Lymphoma, Non-Hodgkin
Inici:
15/12/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
IFx-Hu2.0 Expanded Access Program
Morphogenesis Inc.
Carcinoma; Carcinoma, Merkel Cell; Carcinoma, Squamous Cell; Melanoma; Neuroendocrine Tumors; Skin Neoplasms
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I Study of B006 in Patients with Lymphoma
Shanghai Pharmaceuticals Holding Co.
Hodgkin Disease; Hodgkin Lymphoma; Lymphoma, Large-Cell, Anaplastic; Lymphoma, Non-Hodgkin
Inici:
01/01/1900
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Randomized, Open-label, Single-dose, Two-preparation, Two-sequence, Two-cycle Crossover, Bioequivalence Study of Doxorubicin Hydrochloride Liposome ...
(Other Hospital/Academic/Medical Center)
China Medical System Holdings/Shenzhen Kangzhe Pharmaceutical Co.
Breast Neoplasms; Carcinoma, Ovarian Epithelial; Ovarian Cancer; Ovarian Neoplasms
Inici:
28/07/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase I/II, Open-label, Dose-exploration and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NTX-301 ...
Pinotbio
Xennials Therapeutics Australia
Glioblastoma; Glioma; Neoplasms, Unknown Primary; Ovarian Cancer; Ovarian Neoplasms; Urethral Neoplasms; Urinary Bladder Neoplasms
Inici:
25/08/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Phase 1 Double-Blind, Placebo-Controlled, Single- and Multiple-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynami...
Johnson & Johnson/Janssen Pharmaceuticals/Momenta Pharmaceuticals
Anemia; Myasthenia Gravis; Systemic Lupus Erythematosus; Unspecified
Inici:
21/05/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
A Multicenter, Open-label, Single-arm, Phase Ib Study to Evaluate Safety and Efficacy of Mitoxantrone Hydrochloride Liposome Injection in Subjects Wit...
CSPC Pharmaceutical Group Co./CSPC ZhongQi Pharmaceutical Technology Co.
Head and Neck Neoplasms
Inici:
29/06/2021
Reclutament:
01/01/1900
Final:
Estat:
En procés
Detalls / Registre
Sequential Infusion of CD19 and BCMA Chimeric Antigen Receptor T Cells to Improve Alloimmune-mediated Platelet Transfusion Refractoriness in Patients ...
(Other Hospital/Academic/Medical Center)
Shanghai Unicar-Therapy Bio-medicine Technology Co.
Acute Myelocytic Leukemia; Chronic Lymphocytic Leukemia; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute
Inici:
29/04/2021
Reclutament:
01/01/1900
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